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While Despark can exile any permanent with mana value 4 or greater, there are better options like Anguished Unmaking, which has a broader range of targets but comes with a higher cost
![discard two cards mtg Compulsive Research [Commander 2014] Thirst for Discovery Innistrad:](https://cards.scryfall.io/normal/front/b/1/b1ed095e-6b77-4262-a2fa-d04dde96f9e4.jpg?1782702955)
If youre pitching cards anyway, this turns the downside into value fast, especially in decks like Hashaton, Scarab's Fist in Commander, where youre already discarding creatures for value
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Yorion, Sky Nomad Yorion, the white/blue companion, is legal in Brawl and Commander decks and can be your commander
![discard two cards mtg Compulsive Research [Commander 2014] Thirst for Discovery Innistrad:](https://lookaside.fbsbx.com/lookaside/crawler/media/?media_id=10164024389251004)
There are myriad other thoughts that crossed my mind about this particular setting too, of course
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